Multi-omic definition of metabolic obesity through adipose tissue–microbiome interactions
The expanding landscape of GLP-1 medicines
Lessons in public trust
Autologous multiantigen-targeted T cell therapy for pancreatic cancer: a phase 1/2 trial
Shared and specific blood biomarkers for multimorbidity
Mechanistic insights make cancer cachexia a targetable syndrome
A One Health trial design to accelerate Lassa fever vaccines
Generative AI-based low-dose digital subtraction angiography for intra-operative radiation dose reduction: a randomized controlled trial
When science meets violence
Early successes in colon immunotherapy
Reply to Ludwig, D. S. et al.; Robinson, E. & Forde, C. G.; Wang, Z. & Peng, C.
Malaria vaccine protection against intradermal or venous parasites: a randomized phase 2b human challenge trial
Building a code of conduct for AI-driven clinical consultations
Concerns over conclusions in an ultra-processed food trial
Global, regional, and national burden of chronic respiratory diseases and impact of the COVID-19 pandemic, 1990–2023: a Global Burden of Disease study
Going beyond genomics in precision oncology
Concerns around evidence that food processing should be included in dietary guidance
Political protests, social media use and mental well-being
Real-world clinical utility of comprehensive genomic profiling in advanced solid tumors
Interpersonal conflicts, social media use and depression associated with protests
A multimodal sleep foundation model for disease prediction
Concerns about attributing weight change to processing in a crossover feeding trial
Housing modifications for heat adaptation, thermal comfort and malaria vector control in rural African settlements
Oral splicing modulator branaplam in Huntington’s disease: a phase 2 randomized controlled trial
The impact of an oral purified microbiome therapeutic on the gastrointestinal microbiome
The Italian parliament first to recognize obesity as a chronic and relapsing disease
The ethics of multi-cancer screening
Reduce bureaucracy in clinical trials now
A minimally invasive dried blood spot biomarker test for the detection of Alzheimer’s disease pathology
AI-enabled virtual spatial proteomics from histopathology for interpretable biomarker discovery in lung cancer
Silenced genomes
Navigating difficult ethical decisions in global health
Eliminating opioid prescriptions from outpatient minimally invasive gynecologic surgery: a randomized trial
Blood biomarkers reveal pathways associated with multimorbidity
Author Correction: The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue
Eleven clinical trials that will shape medicine in 2026
People with autism deserve evidence-based policy and care
Building a blueprint for intra-tumoral microbial studies
Advancing equitable and sustainable urban health
Microbial signals in primary and metastatic brain tumors
The physiology of dying.
Characterizing the physiology of circulatory arrest in humans.
Time for the exposome to shape policy.
An implantable system to restore hemodynamic stability after spinal cord injury.
From one to many gene therapies.
Nutrition research must go local
Dementia prevention needs clinical trials
Reduced-energy diet in women with gestational diabetes: the dietary intervention in gestational diabetes DiGest randomized clinical trial
The Future of Medicine.
Health AI poses distinct harms and potential benefits for disabled people.