Menopause age and cancer risk is influenced by rare genetic variants
Cryo-EM structure of the human subcortical maternal complex and the associated discovery of infertility-associated variants
Author Correction: Structural basis for antibody-mediated NMDA receptor clustering and endocytosis in autoimmune encephalitis
Publisher Correction: Structure and activation of the RING E3 ubiquitin ligase TRIM72 on the membrane
Cohesin closes the door on coexpression
AlphaFold3 takes a step toward decoding molecular behavior and biological computation
The RNA world
Mechanisms of transcription and RNA processing
Decoding branch points and unlocking splicing secrets
To slide or not to slide: key role of the hexasome in chromatin remodeling revealed
Membrane-embedded machines
Macrophages need to release the proximal brake to degrade cellular corpses
Future opportunities in solute carrier structural biology
Musings on art and science
Looking back at 30 years of Nature Structural & Molecular Biology
The impact of DNA methylation on CTCF-mediated 3D genome organization
Towards an improved understanding of ubiquitylation
Chemical rewiring of ubiquitination by degraders and their selectivity routes
Ubiquitin in autophagy and non-protein ubiquitination
Turning vaccine design on its head
Breaking the K48-chain: linking ubiquitin beyond protein degradation
Structure of a membrane tethering complex incorporating multiple SNAREs
The Ruminococcus bromii amylosome protein Sas6 binds single and double helical α-glucan structures in starch
Design of complicated all-α protein structures
DNA looping mediates cooperative transcription activation
Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes
CAND1 inhibits Cullin-2-RING ubiquitin ligases for enhanced substrate specificity
UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4
Correction to: Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD (Nature Structural & Molecular Biology, (2023), 30, 11, (1628-1639), 10.1038/s41594-023-01095-4)
Structural basis of the subcortical maternal complex and its implications in reproductive disorders
Pioneer factor Pax7 initiates two-step cell-cycle-dependent chromatin opening
Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus
Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing
DNA methylation restricts coordinated germline and neural fates in embryonic stem cell differentiation
General transcription factor from Escherichia coli with a distinct mechanism of action
THEMIS is a substrate and allosteric activator of SHP1, playing dual roles during T cell development
Auto-suppression of Tet dioxygenases protects the mouse oocyte genome from oxidative demethylation
Quantitative analysis of transcription start site selection reveals control by DNA sequence, RNA polymerase II activity and NTP levels
Celebrating Nature Structural & Molecular Biology's 30th anniversary
Structural biology in the Anthropocene epoch
NSMB's 30th anniversary: shining a light on the invisible
Communities in structural biology
Thinking outside the chromosome: epigenetic mechanisms in non-canonical chromatin species
Mechanical disengagement of the cohesin ring
EMC rectifies the topology of multipass membrane proteins
3D Enhancer–promoter networks provide predictive features for gene expression and coregulation in early embryonic lineages
Structural insights into the iron nitrogenase complex
Transport and inhibition mechanism of the human SGLT2–MAP17 glucose transporter
Complete set of the Atg8–E1–E2–E3 conjugation machinery forms an interaction web that mediates membrane shaping
Structural basis of branching during RNA splicing