Journal & Article

Biological and Statistical Physics

I/F
# Journal I/F

NATURE STRUCTURAL & MOLECULAR BIOLOGY

Membrane-embedded machines Macrophages need to release the proximal brake to degrade cellular corpses Future opportunities in solute carrier structural biology Musings on art and science Looking back at 30 years of Nature Structural & Molecular Biology The impact of DNA methylation on CTCF-mediated 3D genome organization Towards an improved understanding of ubiquitylation Chemical rewiring of ubiquitination by degraders and their selectivity routes Ubiquitin in autophagy and non-protein ubiquitination Turning vaccine design on its head Breaking the K48-chain: linking ubiquitin beyond protein degradation Structure of a membrane tethering complex incorporating multiple SNAREs The Ruminococcus bromii amylosome protein Sas6 binds single and double helical α-glucan structures in starch Design of complicated all-α protein structures DNA looping mediates cooperative transcription activation Synovial sarcoma X breakpoint 1 protein uses a cryptic groove to selectively recognize H2AK119Ub nucleosomes CAND1 inhibits Cullin-2-RING ubiquitin ligases for enhanced substrate specificity UBE2A and UBE2B are recruited by an atypical E3 ligase module in UBR4 Correction to: Live-cell three-dimensional single-molecule tracking reveals modulation of enhancer dynamics by NuRD (Nature Structural & Molecular Biology, (2023), 30, 11, (1628-1639), 10.1038/s41594-023-01095-4) Structural basis of the subcortical maternal complex and its implications in reproductive disorders Pioneer factor Pax7 initiates two-step cell-cycle-dependent chromatin opening Structural insight into the assembly and working mechanism of helicase-primase D5 from Mpox virus Structural basis of the human NAIP/NLRC4 inflammasome assembly and pathogen sensing DNA methylation restricts coordinated germline and neural fates in embryonic stem cell differentiation General transcription factor from Escherichia coli with a distinct mechanism of action THEMIS is a substrate and allosteric activator of SHP1, playing dual roles during T cell development Auto-suppression of Tet dioxygenases protects the mouse oocyte genome from oxidative demethylation Quantitative analysis of transcription start site selection reveals control by DNA sequence, RNA polymerase II activity and NTP levels Celebrating Nature Structural & Molecular Biology's 30th anniversary Structural biology in the Anthropocene epoch NSMB's 30th anniversary: shining a light on the invisible Communities in structural biology Thinking outside the chromosome: epigenetic mechanisms in non-canonical chromatin species Mechanical disengagement of the cohesin ring EMC rectifies the topology of multipass membrane proteins 3D Enhancer–promoter networks provide predictive features for gene expression and coregulation in early embryonic lineages Structural insights into the iron nitrogenase complex Transport and inhibition mechanism of the human SGLT2–MAP17 glucose transporter Complete set of the Atg8–E1–E2–E3 conjugation machinery forms an interaction web that mediates membrane shaping Structural basis of branching during RNA splicing Shifted PAMs generate DNA overhangs and enhance SpCas9 post-catalytic complex dissociation (Vol 30, Pg 1707, 2023) Nucleosome-bound NR5A2 structure reveals pioneer factor mechanism by DNA minor groove anchor competition The open gate of the AMPA receptor forms a Ca2+ binding site critical in regulating ion transport Cryo-EM structure of human sphingomyelin synthase and its mechanistic implications for sphingomyelin synthesis The CNK-HYP scaffolding complex promotes RAF activation by enhancing KSR-MEK interaction Deadenylation kinetics of mixed poly(A) tails at single-nucleotide resolution Protein-intrinsic properties and context-dependent effects regulate pioneer factor binding and function Structural basis of pH-dependent activation in a CLC transporter (jan, 10.1038/s41594-023-01210-5, 2023) Single-nucleoid architecture reveals heterogeneous packaging of mitochondrial DNA Just how big is the ubiquitin system?