Pathway Deep in the Brain Makes It Resilient After Injury
For days, and even years, after someone suffers a stroke or traumatic brain injury, they have an increased risk of developing epilepsy. Now, researchers at Gladstone Institutes discovered that star-shaped cells called astrocytes in the thalamus play a key role in making mice with brain injuries susceptible to seizures. The team also analyzed human post-mortem brain tissue and showed that the same cells identified in mice might be altered in the thalamus of people affected by brain injury and stroke. The findings, published in the journal Science Translational Medicine, suggest that targeting a protein in these cells could prevent the long-term damage that follows brain injury. “In the aftermath of brain injuries, the thalamus has been relatively understudied compared to other brain regions,” says Jeanne Paz, PhD, an associate investigator at Gladstone and senior author of the new study. “I’m hoping this is just the beginning of many new lines of research about how important this region is in determining how we can help the brain be resilient to consequences of injuries.”
Study evaluates the effectiveness of universal school-based mindfulness training
School-based mindfulness training, universally applied across the UK in a bid to boost teen mental health and wellbeing, probably isn't warranted, suggest the results of a cluster of 5 studies, published online in a special issue of Evidence-Based Mental Health. The overall evidence for the effectiveness of the approach, as delivered in its current format, is weak, show the latest studies from the My Resilience in Adolescence (MYRIAD) trial, involving thousands of teens and hundreds of teachers across the UK. And while there are some benefits for teachers, and the 'school climate'-;the academic, community, safety and structural features of a school-;the effects are short-lived, the findings indicate.
New study reveals where memory fragments are stored
While the overall experience is stored in the hippocampus, the brain structure long considered the seat of memory, individual details are parsed and stored elsewhere, in the prefrontal cortex. This separation ensures that, in the future, exposure to any individual cue is sufficient to activate the prefrontal cortex, which then accesses the hippocampus for recall of the whole memory.