Researchers discover new classes of RNA for learning and memory

Researchers have discovered a new way ribonucleic acid (RNA) impacts fear-related learning and memory. Researchers demonstrated that a noncoding RNA known as Gas5 coordinates the trafficking and clustering of RNA molecules inside the long processes of neurons, and orchestrating neuronal excitability in real time that contributes to learning and memory. This study builds on earlier findings this yearwhich identified a separate population of learning-related RNAs that accumulate near the synapse -- the junction between neurons that allow them to communicate. In that paper, published in theJournal of Neuroscience, they uncovered several new synapse-specific RNA that harbour a specific chemical ..

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Distinct brain activity triggered by memories of trauma

It is well known that people who have lived through traumatic events like sexual assault, domestic abuse, or violent combat can experience symptoms of post-traumatic stress disorder (PTSD), including terrifying flashbacks, severe anxiety, and uncontrollable thoughts about the incident. But what exactly happens in the brains of PTSD patients as they recall these traumatic events? Are they remembered the same way as, say, the loss of a beloved pet -- or, for that matter, a relaxing walk on the beach?

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Pulling an all-nighter? Don't follow with an important decision

With little insight into the impact of a lack of sleep on risky decision-making at the neuroimaging level, researchers found a 24-hour period of sleep deprivation significantly impacted individuals' decision-making processes by dampening neural responses to the outcomes of their choices.

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A small molecule blocks aversive memory formation, providing a potential treatment target for depression

Depression is one of the most common mental illnesses in the world, but current anti-depressants have yet to meet the needs of many patients. Neuroscientists recently discovered a small molecule that can effectively alleviate stress-induced depressive symptoms in mice by preventing aversive memory formation with a lower dosage, offering a new direction for developing anti-depressants in the future.

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Smaller hippocampus linked to cognitive decline

With the rise of new drugs that can target the amyloid-beta plaques in the brain that are an early sign of Alzheimer's disease, new ways are needed to determine whether memory loss and thinking problems are due to Alzheimer's disease or another neurodegenerative disorder. A new study shows that shrinkage in the hippocampus area of the brain is associated with cognitive decline, even in people who don't have amyloid plaques in the brain. The hippocampus plays a role in memory.

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Reducing 'vivid imagery' that fuels addiction cravings

New research shows promise in treating addiction cravings by combining eye movements and guided instructions to process memories. Researchers transformed dysfunctional memories stored in the brain through processing and integration. EMDR was as effective as cognitive behavioral therapy for cravings with the combination of both resulting in more reduction in craving than cognitive behavioral therapy (CBT) alone. Both groups (experimental group and control group using only CBT) had clinically significant reductions in cravings, repetitive negative thoughts, and irrational cognitions, with the experimental group showing greater decreases overall.

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Stunting in infancy linked to differences in cognitive and brain function

New research shows that children who are too short for their age can suffer reduced cognitive ability from as early as six months old. Researchers compared the 'visual working memory'in children who had stunted growth with those having typical growth. They found that the visual working memory of infants with poor physical growth was disrupted, making them more easily distracted and setting the stage for poorer cognitive ability one year later.

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New study reveals role of hippocampus in two functions of memory

For the first time, a new study in rats teases apart the role of the hippocampus in two functions of memory -- one that remembers associations between time, place and what one did, and another that allows one to predict or plan future actions based on past experiences.

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Study examines role of working memory, cognitive functions in English learners learning to write

A new study has examined the role of several cognitive functions in young students learning to write English, their second language. The study conducted a battery of cognitive tests, gauged the writing skills of the students and then tested the functions again. Working memory, or how we store thoughts we want to convey, was shown to be the most significant predictor of writing ability. Other cognitive functions like phonological awareness and oral language development increased as the students aged, but were not associated with improved writing. The results not only help us understand how English learners, a growing population, learn to write, but can help educators design better interventio..

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